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Permax Users - On January 3, 2007 new studies came out linking Permax with heart valve disease. Permax is a drug used to treat Parkinson's Disease that has been show to have direct links to an increase in heart valve leaks in patient taking the drug.

The attorneys at Handler, Henning & Rosenberg, LLP are here to help you. If you or a loved one are taking Permax for Parkinson's or other related illness call the attorneys at Handler, Henning & Rosenberg, LLP are here to help you with your Permax claim.

Permax Study links to Valve Damage

A study by Italian researchers found that approximately 1 in 4 Parkinson's patients taking Permax had moderate to severe heart valve related damage.

In a German study, doctors established that Permax users were five to seven times more likely to have leaky heart valves than those on other types of Parkinson's medications. Both studies can be found in the New England Journal of Medicine.

Dr. Renzo Zanettini and others at the Instituti Clinici di Perfezionamento in Milan obtained echocardiogram images of the hearts of 155 patients taking various Parkinson's medications and a comparison group of 90 healthy people.

Moderate to severe valve problems were seen in 29% those on Permax.
In the German study, Dr. Rene Schade and associates in Berlin and in Montreal used records from over 11,400 Parkinson's patients in the United Kingdom. The rate of newly diagnosed leaky valves was increased among Permax users.

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Pfizer Clarifies Permax Heart valve claims

Permax (generic: cabergoline) manufactured by Pfizer Inc., gained approval by the FDA on December 23, 1996. Permax is used for Parkinson’s in other countries but is approved in this country only for a hormonal disorder, hyperprolactinemia. People with Parkinson’s often take doses 20 to 40 times higher than patients with hormone disorders.who take Dositnex. 

Dr. Michael Berelowitz, senior vice president of Pfizer, which makes Permax, said the company had received fewer than 100 reports of valve problems from the drug, mostly in people with Parkinson’s.

The two new reports involve only Parkinson’s. The results should not be applied to patients who take Permax for the hormone disorder, because they take far smaller doses of the drug than do patients with Parkinson’s, said Dr. David L. Kleinberg, a professor of medicine and director of the neuroendocrine unit at New York University’s medical school. Many doctors consider it the best drug for the problem.

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Let the Law Offices of Handler, Henning & Rosenberg, LLP handle your Permax case.  If you or someone you love are taking Permax and have Parkinson's Disease, the attorneys at Handler, Henning & Rosenberg, LLP are here to help you. Call today to discus your Permax claim.